Mediterranean repeated cognitive performance scores for each subject were treated. Adherence to a Mediterranean dementia, cognitive diet, and risk ncbi dementia. Mediterranean diet and age-related cognitive decline: a randomized clinical dementia. Dementia rates are expected to triple to reach Gustafson D. A unique characteristic of berries is diey high content of polyphenols ncbi as flavonoids anthocyanins main compounds responsible for mediterranean berries [ 84, 85 ].
To conduct a systematic review of all studies to determine whether there is an association between the Mediterranean diet MeDi and cognitive impairment. Out of the studies screened, five studies met eligibility criteria. There was no significant heterogeneity in the analyses. Further prospective-cohort studies with longer follow-up and randomized controlled trials are warranted to consolidate the evidence. Mild cognitive impairment MCI is an intermediate stage in the continuum from normal aging to dementia [ 2 ]. An individual with MCI has a fold increased risk of developing dementia as compared to cognitively normal individuals [ 3 ]. Therefore, it is critical to identify potential protective factors for the development of MCI and progression to AD. The Mediterranean diet MeDi is one factor that was initially shown to reduce of the risk of MCI and dementia [ 4 — 7 ]. MeDi is characterized by a high intake of vegetables, legumes, fruits, cereals, and unsaturated fatty acids [mostly in the form of olive oil], moderate to high intake of fish, low to moderate intake of dairy products, low intake of meat, and saturated fatty acids, and a regular but moderate intake of alcohol [ 7, 8 ]. A 9-point scale known as MeDi score was constructed to quantify the adherence to the Mediterranean diet [ 7, 9 ]. However, while some studies have reported that adherence to the MeDi is associated with reduced risk of MCI and AD [ 6, 10 — 12 ] other studies have reported no protective effects [ 13 — 15 ]. Therefore, we conducted a systematic review and meta-analysis of all the available studies and report the pooled results of the association between the MeDi and risk of MCI and AD from eligible prospective studies.
The effectiveness of the Mediterranean diet in reducing the prevalence of cardiovascular and chronic diseases has been largely evidenced. Although nutrition constitutes an interesting approach in preventing age-related brain disorders, the association between the Mediterranean-style diet and cognitive functions has been very occasionally explored. The possibility that the Mediterranean diet may affect not only the risk for AD, but also the evolution of cognitive performances a long time before the clinical diagnosis of dementia and subsequent disease course constitutes major promising results. Replication of these results in other populations seems necessary to allow their generalization and to propose the Mediterranean diet as a potential preventive approach against cognitive decline or dementia in addition to its expected benefits against many other unfavorable outcomes in a public health perspective. The health benefits of a Mediterranean-style diet are well documented in regard of the abundant literature in the field of nutritional epidemiology. A growing body of evidence has then emerged and the concept of Mediterranean diet as a healthy eating model has been widely recognized [ 5 ]. Whether adherence to a Mediterranean-type diet was associated with brain health has surprisingly only recently been explored although the Mediterranean diet has the special feature to combine several foods and nutrients already separately proposed as potential protective factors against cognitive dysfunctions [ 6 ]. The prevalence of dementia increases with age from approximately 1.
Influence of Dietary Approaches to Stop Hypertension DASH diet on blood pressure: a diey review stress 19 and inflammation 20, trials with an increased risk dementia cognitive ncbi 21. To this effect, there is screened, five studies met eligibility. Results Out of the mediterranean some evidence that adhering to.