Potential preventive effects of ADF on cardiovascular disease need to be confirmed by future investigations. J Acad Nutr Diet. Potential beneficial effects of IF on dyslipidaemia are controversial [ 13, 27, 28 ]. Menu HOME. Source: University of Sydney. Any time you restrict calories, your body reacts. Notably, NAFLD is regarded as an even stronger predictor for the development of T2DM then waist circumference or obesity [ 7 ], and the degree of histologic liver damage is directly related to the presence of diabetes in morbidly obese patients [ 8 ]. In the current study, the scientists looked for liver cell genetic activity differences that were caused by fasting.
One fascinating implication from this finding is the potential development of a drug that could specifically target this protein, recreating the effect of fasting on the liver, but without actually needing to fast. View all the latest top news in the environmental sciences, or browse the topics below. We’ll assume you’re ok with this, but you can opt-out if you wish. Half of the subjects , Related Stories. Browning J. Stress molecule reduces the absorption of fatty acids in the liver In the current study, the scientists looked for liver cell genetic activity differences that were caused by fasting. Harvie M, Howell A. Compared with baseline, there were no significant differences in total cholesterol, HDL, LDL and triglycerides among the 3 groups. Most people can benefit from repeated intermittent fasting cycles. ScienceDaily, 9 May Intermittent fasting IF is a novel weight loss regimen that has been steadily growing in popularity over the past decade [ 6, 7 ].
Metrics details. Alternate-day fasting ADF is a novel diet therapy that may achieve reduction in body weight and improvement of dyslipidaemia, but the impact of this diet on patients with non-alcoholic fatty liver disease NAFLD remains unknown. Changes in fat free mass, HDL, LDL, fasting insulin, glucose, liver stiffness, and systolic or diastolic blood pressure did not differ between the groups. Potential preventive effects of ADF on cardiovascular disease need to be confirmed by future investigations. ChiCTR, this trial was retrospectively registered on July 10, Peer Review reports. Non-alcoholic fatty liver disease NAFLD is a spectrum of liver disease characterised by steatosis, a deposition of ectopic fat in the liver, that in contrast to alcoholic fatty liver disease cannot be explained by excessive alcohol consumption. Lifestyle modifications including diet and exercise are considered the initial treatment of choice with the aim to reduce weight gain and the risk of developing insulin resistance and metabolic syndrome [ 4, 5 ].